Health Research

Why is health research important?

What we know about cancer changes over time as more research is done. Health research has led to medical treatments and health programs available today. These advances have helped the five-year survival rate for all cancers to rise from 52% to 68% over the past 20 years.

The search for better ways to prevent, diagnose, and treat human diseases is ongoing. It requires the active participation of patients, carers, and healthy people.

Why participate in research?

The involvement of patients, carers, and healthy people in research is necessary to help researchers learn more about a disease and ways to treat it. Most people diagnosed with cancer who decide to participate in research do so because they want to help improve outcomes for others in the future, as well as for themselves.

Adults and children can participate in different ways, including:

• consenting to their medical records being accessed
• completing surveys
• trialing treatments
• agreeing to be examined regularly by health professionals
• allowing samples taken during tests or treatment to be used for research.

Who can participate in research?

All research studies, including clinical trials, have guidelines setting out who can participate. Both adults and children can take part, but children under the age of 18 need a parent’s or guardian’s permission. Most cancer research involves current patients. However, some studies target former patients, carers, family members, people at risk of cancer, or people who have not had the disease.

It is important that people of all ages and social, economic, and racial backgrounds take part so the results reflect Australia’s diverse population. Deciding to take part can help you weigh up the benefits and risks of being in a study, and answer other questions you may have. Learn more about participating in clinical trials or other types of cancer research.

Where does research take place?

Research is carried out in many places, including hospitals, cancer centers, laboratories, and universities. Sometimes you can participate from home – you might have treatment or medicines mailed to you, or you might be asked to fill in a survey or complete a telephone interview.

Is research safe?

Understandably, people want to know if there are any risks to participating in a study. Researchers must follow strict guidelines to make sure studies are as safe as possible for everyone involved. This is called their duty of care.

All studies need to be approved by human research ethics committees before they can begin. As part of this process, researchers identify risks that might occur, such as possible side effects. They must also explain how they’ll monitor these risks and what will be done if problems occur. For more on this, see Regulation of clinical research.

Who funds cancer research?

Funding comes from many sources. These sources include:

National Health and Medical Research Council (NHMRC) – This is the Australian Government’s main funding body for medical research. The NHMRC awards grants to researchers based on their ability to investigate important questions about human health. The NHMRC also administers the government’s Medical Research Future Fund.

Cancer charities – State and territory Cancer Councils and other charities receive donations from the public and grants from both public and private sectors. This funds their own research and allows them to support research carried out by other institutions financially.

Government bodies – Other Australian, state, and territory government agencies offer a competitive grants program to fund research and to employ cancer trial staff.

Medical research institutions and clinics – These sometimes use their own resources to support research.

Private sector (industry-funded) – Companies producing medicines and medical equipment run trials to check safety and effectiveness before applying for licenses to sell these products. Private companies may also fund research in partnership with a university or other research institution, or for goodwill (philanthropic) reasons.

The National Health and Medical Research Council (NHMRC)

The NHMRC’s mission is to build a healthy Australia. It does this by:

• developing health advice for the general community and health professionals
• funding research projects ranging from basic through to clinical, public health and health services research
• supporting the translation of research findings into clinical practice.

The NHMRC also produces guidelines outlining ethical conduct in research.

Ethics committees must follow these guidelines and report to the NHMRC every year. For more on this, download the National Statement on Ethical Conduct in Human Research (2007) (updated 2018).

What is a conflict of interest?

A conflict of interest may arise in any research project. This means the interests of an organization or researcher could influence the outcome of the research. Researchers are required to disclose any possible or actual conflicts of interest. All research projects should include details of how a conflict of interest will be managed.